Rat A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) Protein

Este producto es parte de ADAMTS7 - ADAM metallopeptidase with thrombospondin type 1 motif 7
Rat A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) Protein

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935106861

info@markelab.com

Precio

234€ (10 µg)

Protein ADAMTS7

proveedor

Abbexa

reference

abx065080

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).


Background

ADAMTS7 (A Disintegrin And Metalloproteinase with Thrombospondin Motifs 7) is another member of the ADAMTS family of proteases. Like other ADAMTS proteins, ADAMTS7 contains multiple domains, including a metalloproteinase domain, a disintegrin-like domain, and thrombospondin type-1 (TSP-1) motifs. ADAMTS7 is expressed in various tissues, including skeletal muscle, heart, brain, and cartilage. Its expression pattern suggests roles in tissue development, maintenance, and homeostasis. ADAMTS7 is implicated in various physiological processes, particularly in extracellular matrix (ECM) remodeling. It plays a role in the turnover and organization of ECM components, including proteoglycans and collagens. Additionally, ADAMTS7 has been linked to angiogenesis, inflammation, and wound healing.Dysregulation of ADAMTS7 has been associated with several diseases and conditions. In particular, ADAMTS7 has been implicated in osteoarthritis, where it may contribute to cartilage degradation and joint inflammation. Studies have also linked ADAMTS7 to atherosclerosis, where it may play a role in plaque formation and vascular remodeling.

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 15.8 kDa Observed MW (SDS-PAGE): 18 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val444-Pro575 Tag: N-terminal His tag


purity

> 97%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ADAMTS7


dry ice

No


availability

Shipped within 5-7 working days.


alias

COMPase, Type 1 Motif 7,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7,ADAMTS-7,ADAM-TS 7


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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reference

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Tested Applications

WB, SDS-PAGE

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234€ (10 µg)

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