Human A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) Protein

221€ (10 µg)
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935106861
info@markelab.com
name
Human A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065079
tested applications
WB, SDS-PAGE
Description
Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) |
Host | E. coli |
Origin | Human |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 12.3 kDa Observed MW (SDS-PAGE): 15 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val1589-Arg1686 Tag: N-terminal His tag |
Purity | > 97% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9UKP4 |
Alias | COMPase, Type 1 Motif 7,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7,ADAMTS-7,ADAM-TS 7 |
Background | Protein ADAMTS7 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ADAMTS7 (A Disintegrin And Metalloproteinase with Thrombospondin Motifs 7) is another member of the ADAMTS family of proteases. Like other ADAMTS proteins, ADAMTS7 contains multiple domains, including a metalloproteinase domain, a disintegrin-like domain, and thrombospondin type-1 (TSP-1) motifs. ADAMTS7 is expressed in various tissues, including skeletal muscle, heart, brain, and cartilage. Its expression pattern suggests roles in tissue development, maintenance, and homeostasis. ADAMTS7 is implicated in various physiological processes, particularly in extracellular matrix (ECM) remodeling. It plays a role in the turnover and organization of ECM components, including proteoglycans and collagens. Additionally, ADAMTS7 has been linked to angiogenesis, inflammation, and wound healing.Dysregulation of ADAMTS7 has been associated with several diseases and conditions. In particular, ADAMTS7 has been implicated in osteoarthritis, where it may contribute to cartilage degradation and joint inflammation. Studies have also linked ADAMTS7 to atherosclerosis, where it may play a role in plaque formation and vascular remodeling.
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