Rat A Disintegrin And Metalloprotease 1 (ADAM1) Protein

234€ (10 µg)
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935106861
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name
Rat A Disintegrin And Metalloprotease 1 (ADAM1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167719
tested applications
WB, SDS-PAGE
Description
ADAM Protein is a recombinant Rat protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | A Disintegrin And Metalloprotease 1 (ADAM1) |
Host | E. coli |
Origin | Rat |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 32.4 kDa Observed MW (SDS-PAGE): 37 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser463-Gly727 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 95% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | Fertilin α,fertilin alpha,FTNAP; PH-30a; Ftna; ADAM1P,ADAM-1,Adam1a |
Background | Protein ADAM1 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
A Disintegrin and Metalloproteinase Domain 1 (ADAM1) is a member of the ADAM family of proteins, characterized by their roles in cell adhesion, migration, and proteolysis. ADAM1 is primarily expressed in the testis and is involved in sperm-egg interactions during fertilization. It is localized to the surface of spermatozoa and is essential for sperm binding to the zona pellucida of the oocyte. ADAM1 contains multiple domains, including a metalloproteinase domain, which is responsible for proteolytic activity, and a disintegrin domain, involved in cell-cell and cell-matrix interactions. Dysregulation of ADAM1 expression or function may impact male fertility and reproductive health. Research into ADAM1's molecular mechanisms and interactions is ongoing, with potential implications for contraceptive development and fertility treatments.
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