Rat A Disintegrin And Metalloprotease 1 (ADAM1) Protein

Este producto es parte de ADAM1 - A disintegrin and metallopeptidase domain 1
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234€ (10 µg)

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935106861
info@markelab.com
name
Rat A Disintegrin And Metalloprotease 1 (ADAM1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167719
tested applications
WB, SDS-PAGE

Description

ADAM Protein is a recombinant Rat protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
A Disintegrin And Metalloprotease 1 (ADAM1)
Host
E. coli
Origin
Rat
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 32.4 kDa  Observed MW (SDS-PAGE): 37 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Ser463-Gly727
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
Fertilin α,fertilin alpha,FTNAP; PH-30a; Ftna; ADAM1P,ADAM-1,Adam1a
Background
Protein ADAM1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

A Disintegrin and Metalloproteinase Domain 1 (ADAM1) is a member of the ADAM family of proteins, characterized by their roles in cell adhesion, migration, and proteolysis. ADAM1 is primarily expressed in the testis and is involved in sperm-egg interactions during fertilization. It is localized to the surface of spermatozoa and is essential for sperm binding to the zona pellucida of the oocyte. ADAM1 contains multiple domains, including a metalloproteinase domain, which is responsible for proteolytic activity, and a disintegrin domain, involved in cell-cell and cell-matrix interactions. Dysregulation of ADAM1 expression or function may impact male fertility and reproductive health. Research into ADAM1's molecular mechanisms and interactions is ongoing, with potential implications for contraceptive development and fertility treatments. 

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