Ras-Related Protein Rab-4B (RAB4B) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Ras-Related Protein Rab-4B (RAB4B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx030694
tested applications
ELISA, WB
Description
RAB proteins, such as RAB4B, are members of the RAS superfamily of small GTPases that are involved in vesicular trafficking (He et al., 2002 [PubMed 12450215]).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ras-Related Protein Rab-4B (RAB4B) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61018 |
| Alias | Ras-related protein Rab-4B |
| Background | Antibody anti-RAB4B |
| Status | RUO |
Descripción
RAB4B, member RAS oncogene family (RAB4B) is closely related to RAB4A and also regulates vesicular trafficking and endosomal dynamics RAB4B is involved in recycling endosomal trafficking, helping to regulate the movement of endosomes and proteins between cellular compartments and maintaining membrane integrity It plays a role in receptor recycling and in the trafficking of various membrane-bound proteins, thereby affecting processes like cell adhesion, migration, and signal transduction RAB4B has been shown to influence cell surface protein composition, impacting the function of key receptors and signaling pathways Dysregulation of RAB4B has been linked to several diseases, including cancer, where improper vesicular recycling can contribute to uncontrolled cell proliferation and metastasis Additionally, RAB4B has roles in other cellular processes such as autophagy and immune cell trafficking, further underscoring its importance in maintaining cellular homeostasis and function
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