935106861
info@markelab.com
Precio
675€ (100 µg)
Detects ~24 kDa. Does not show cross reactivity to RAB3A, RAB3B, or RAB3C.
RAB3D, member RAS oncogene family (RAB3D), another member of the RAB3 family, is also involved in regulating vesicular trafficking and exocytosis RAB3D is particularly important in secretory cells, where it mediates the transport and release of secretory vesicles, including those in endocrine and neuronal cells It plays a role in processes such as insulin secretion in pancreatic cells and neurotransmitter release in neurons through synaptic vesicle recycling RAB3D is crucial for maintaining the proper release of substances from cells, and its dysfunction can lead to a variety of diseases related to impaired vesicle dynamics, including metabolic disorders and neurological diseases Similar to other RAB3 proteins, RAB3D is essential for normal synaptic function, and abnormalities in its activity can contribute to conditions like epilepsy and metabolic syndromes Disruptions in RAB3D’s function further highlight its significance in the regulation of cellular secretion and signaling pathways, making it a potential target for therapeutic interventions in neurological and metabolic diseases
Primary Antibodies
Monoclonal
Human, Mouse, Rat
Ras-Related Protein Rab-3D (RAB3D)
Mouse
PerCP
WB
Purified by Protein G.
PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
100 µg
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
RAB3D
No
Please enquire.
GOV,D2-2,RAB16,RAD3D,Ras-related protein Rab-3D
NP_004274
This product is for research use only.
Protein transport. Probably involved in regulated exocytosis(By similarity).
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