RAB3D, Member RAS Oncogene Family (RAB3D) Antibody
195€ (20 µl)
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935106861
info@markelab.com
name
RAB3D, Member RAS Oncogene Family (RAB3D) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx126450
tested applications
ELISA, WB
Description
RAB3D Antibody is a Rabbit Polyclonal against RAB3D.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB3D, Member RAS Oncogene Family (RAB3D) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95716 |
| Gene ID | 9545 |
| NCBI Accession | NP_004274.1 |
| Alias | GOV,D2-2,RAB16,RAD3D,Ras-related protein Rab-3D |
| Background | Antibody anti-RAB3D |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
RAB3D, member RAS oncogene family (RAB3D), another member of the RAB3 family, is also involved in regulating vesicular trafficking and exocytosis RAB3D is particularly important in secretory cells, where it mediates the transport and release of secretory vesicles, including those in endocrine and neuronal cells It plays a role in processes such as insulin secretion in pancreatic cells and neurotransmitter release in neurons through synaptic vesicle recycling RAB3D is crucial for maintaining the proper release of substances from cells, and its dysfunction can lead to a variety of diseases related to impaired vesicle dynamics, including metabolic disorders and neurological diseases Similar to other RAB3 proteins, RAB3D is essential for normal synaptic function, and abnormalities in its activity can contribute to conditions like epilepsy and metabolic syndromes Disruptions in RAB3D’s function further highlight its significance in the regulation of cellular secretion and signaling pathways, making it a potential target for therapeutic interventions in neurological and metabolic diseases
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