RAB3D, Member RAS Oncogene Family (RAB3D) Antibody
292.5€ (80 µl)
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Name
RAB3D, Member RAS Oncogene Family (RAB3D) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx027281
Tested Applications
ELISA, WB, IHC, FCM
Description
RAB3D is a protein transport. Probably involved in regulated exocytosis (By similarity).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: RAB3D, Member RAS Oncogene Family (RAB3D) Immunogen: KLH-conjugated synthetic peptide between 185-212 amino acids from the C-terminal region of human RAB3D. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 24.3 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95716 |
| Alias | GOV,D2-2,RAB16,RAD3D,Ras-related protein Rab-3D |
| Background | Antibody anti-RAB3D |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RAB3D, member RAS oncogene family (RAB3D), another member of the RAB3 family, is also involved in regulating vesicular trafficking and exocytosis RAB3D is particularly important in secretory cells, where it mediates the transport and release of secretory vesicles, including those in endocrine and neuronal cells It plays a role in processes such as insulin secretion in pancreatic cells and neurotransmitter release in neurons through synaptic vesicle recycling RAB3D is crucial for maintaining the proper release of substances from cells, and its dysfunction can lead to a variety of diseases related to impaired vesicle dynamics, including metabolic disorders and neurological diseases Similar to other RAB3 proteins, RAB3D is essential for normal synaptic function, and abnormalities in its activity can contribute to conditions like epilepsy and metabolic syndromes Disruptions in RAB3D’s function further highlight its significance in the regulation of cellular secretion and signaling pathways, making it a potential target for therapeutic interventions in neurological and metabolic diseases
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