Ras-Related Protein Rab-37 (RAB37) Antibody (FITC)
169€ (20 µg)
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935106861
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name
Ras-Related Protein Rab-37 (RAB37) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx309525
Description
RAB37 Antibody (FITC) is a Rabbit Polyclonal against RAB37 conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ras-Related Protein Rab-37 (RAB37) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96AX2 |
| Gene ID | 326624 |
| NCBI Accession | NP_001006639.1, NM_001006638.2, NP_001157461.1, NM_001163989.1 |
| OMIM | 609956 |
| Alias | Ras-related protein Rab-37 |
| Background | Antibody anti-RAB37 |
| Status | RUO |
Descripción
RAB37, member RAS oncogene family (RAB37) is a small GTPase involved in intracellular vesicular trafficking, particularly in the regulation of endocytosis and exocytosis RAB37 plays a crucial role in the sorting and recycling of proteins between different cellular compartments, ensuring that membrane-bound proteins, lipids, and other cargo are correctly processed and directed to their destinations This function is essential for maintaining cellular homeostasis, signal transduction, and membrane dynamics Additionally, RAB37 has been shown to play a role in autophagy, the process of degrading and recycling damaged or unnecessary cellular components to maintain cellular health Its dysfunction can contribute to several pathologies, including cancer and neurodegenerative diseases, where impaired vesicular trafficking leads to dysregulated cellular signaling and protein accumulation, contributing to disease progression
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