RAB37 antibody

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935106861
info@markelab.com
name
RAB37 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07020
tested applications
ELISA, WB, IHC

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
RAB37, member RAS oncogene family (RAB37)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
25 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q96AX2
Gene ID
326624
Alias
Ras-related protein Rab-37
Background
Antibody anti-RAB37
Status
RUO
Note
Mol. Weight 25 kDa

RAB37, member RAS oncogene family (RAB37) is a small GTPase involved in intracellular vesicular trafficking, particularly in the regulation of endocytosis and exocytosis RAB37 plays a crucial role in the sorting and recycling of proteins between different cellular compartments, ensuring that membrane-bound proteins, lipids, and other cargo are correctly processed and directed to their destinations This function is essential for maintaining cellular homeostasis, signal transduction, and membrane dynamics Additionally, RAB37 has been shown to play a role in autophagy, the process of degrading and recycling damaged or unnecessary cellular components to maintain cellular health Its dysfunction can contribute to several pathologies, including cancer and neurodegenerative diseases, where impaired vesicular trafficking leads to dysregulated cellular signaling and protein accumulation, contributing to disease progression

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