Ras-Related Protein Rab-37 (RAB37) Antibody

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357.5€ (100 µg)

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935106861
info@markelab.com
name
Ras-Related Protein Rab-37 (RAB37) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx036499
tested applications
ELISA, WB

Description

Rabbit Polyclonal against the RAB37 protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Ras-Related Protein Rab-37 (RAB37)
Immunogen: Recombinant fragment corresponding to 31-219 AA of human RAB37.
Host
Rabbit
Reactivity
Human
Assay Type
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml.
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Observed MW: 25 kDa
Purification
Purified by antigen affinity column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB
Buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
Ras-related protein Rab-37
Background
Antibody anti-RAB37
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

RAB37, member RAS oncogene family (RAB37) is a small GTPase involved in intracellular vesicular trafficking, particularly in the regulation of endocytosis and exocytosis RAB37 plays a crucial role in the sorting and recycling of proteins between different cellular compartments, ensuring that membrane-bound proteins, lipids, and other cargo are correctly processed and directed to their destinations This function is essential for maintaining cellular homeostasis, signal transduction, and membrane dynamics Additionally, RAB37 has been shown to play a role in autophagy, the process of degrading and recycling damaged or unnecessary cellular components to maintain cellular health Its dysfunction can contribute to several pathologies, including cancer and neurodegenerative diseases, where impaired vesicular trafficking leads to dysregulated cellular signaling and protein accumulation, contributing to disease progression

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