Ras-Related Protein Rab-37 (RAB37) Antibody
357.5€ (100 µg)
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935106861
info@markelab.com
name
Ras-Related Protein Rab-37 (RAB37) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx036499
tested applications
ELISA, WB
Description
Rabbit Polyclonal against the RAB37 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ras-Related Protein Rab-37 (RAB37) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Ras-related protein Rab-37 |
| Background | Antibody anti-RAB37 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
RAB37, member RAS oncogene family (RAB37) is a small GTPase involved in intracellular vesicular trafficking, particularly in the regulation of endocytosis and exocytosis RAB37 plays a crucial role in the sorting and recycling of proteins between different cellular compartments, ensuring that membrane-bound proteins, lipids, and other cargo are correctly processed and directed to their destinations This function is essential for maintaining cellular homeostasis, signal transduction, and membrane dynamics Additionally, RAB37 has been shown to play a role in autophagy, the process of degrading and recycling damaged or unnecessary cellular components to maintain cellular health Its dysfunction can contribute to several pathologies, including cancer and neurodegenerative diseases, where impaired vesicular trafficking leads to dysregulated cellular signaling and protein accumulation, contributing to disease progression
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