Ras-Related Protein Rab-13 (RAB13) Antibody
195€ (20 µl)
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935106861
info@markelab.com
name
Ras-Related Protein Rab-13 (RAB13) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx126442
tested applications
ELISA, WB, IF/ICC
Description
RAB13 Antibody is a Rabbit Polyclonal against RAB13.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ras-Related Protein Rab-13 (RAB13) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/1000 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P51153 |
| Gene ID | 5872 |
| NCBI Accession | NP_002861.1 |
| Alias | GIG4,Cell growth-inhibiting gene 4 protein,Ras-related protein Rab-13 |
| Background | Antibody anti-RAB13 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
RAB13, member RAS oncogene family (RAB13) is a small GTPase that regulates vesicular trafficking, specifically in the movement of vesicles from the Golgi to the plasma membrane It is involved in maintaining cell polarity and plays a key role in processes like cell-cell junction formation, especially in epithelial cells RAB13 controls the trafficking of proteins that are important for tight junctions, which are critical for maintaining the integrity of cellular barriers such as those found in epithelial tissues RAB13 also regulates vesicle recycling and the proper localization of receptors and transporters on the cell surface, ensuring efficient cellular signaling It has been implicated in several cellular processes, including cell migration, growth factor signaling, and the regulation of actin cytoskeleton dynamics Disruptions in RAB13 function are associated with a range of diseases, including cancer, where altered vesicle trafficking can promote tumor progression and metastasis Additionally, RAB13 plays a role in the immune system, influencing the trafficking of immune receptors and cytokines
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