Ras-Related Protein Rab-13 (RAB13) Antibody
357.5€ (100 µg)
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Name
Ras-Related Protein Rab-13 (RAB13) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx122434
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the RAB13 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Ras-Related Protein Rab-13 (RAB13) Immunogen: Recombinant fragment corresponding to 2-198 AA of human RAB13. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 23 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC000799 |
| Alias | GIG4,Cell growth-inhibiting gene 4 protein,Ras-related protein Rab-13 |
| Background | Antibody anti-RAB13 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RAB13, member RAS oncogene family (RAB13) is a small GTPase that regulates vesicular trafficking, specifically in the movement of vesicles from the Golgi to the plasma membrane It is involved in maintaining cell polarity and plays a key role in processes like cell-cell junction formation, especially in epithelial cells RAB13 controls the trafficking of proteins that are important for tight junctions, which are critical for maintaining the integrity of cellular barriers such as those found in epithelial tissues RAB13 also regulates vesicle recycling and the proper localization of receptors and transporters on the cell surface, ensuring efficient cellular signaling It has been implicated in several cellular processes, including cell migration, growth factor signaling, and the regulation of actin cytoskeleton dynamics Disruptions in RAB13 function are associated with a range of diseases, including cancer, where altered vesicle trafficking can promote tumor progression and metastasis Additionally, RAB13 plays a role in the immune system, influencing the trafficking of immune receptors and cytokines
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