RAB9B, Member RAS Oncogene Family (RAB9B) Antibody

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364€ (100 µg)

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935106861
info@markelab.com
name
RAB9B, Member RAS Oncogene Family (RAB9B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx237050
tested applications
ELISA, WB, IF/ICC

Description

RAB9B Antibody is a Rabbit Polyclonal against RAB9B.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
RAB9B, Member RAS Oncogene Family (RAB9B)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
≥ 95% (SDS-PAGE)
Purification
Purified by Immunogen Affinity Chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IF/ICC
Buffer
PBS, pH 7.3, with 0.02% Sodium Azide and 50% glycerol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9NP90
Gene ID
51209
OMIM
300285
Alias
RAB9L,Rab-9-like protein,Ras-related protein Rab-9B
Background
Antibody anti-RAB9B
Status
RUO
Note
Concentration: 2 mg/ml - Validity: 12 months.

Descripción

RAB9B, member RAS oncogene family (RAB9B) shares functional similarities with RAB9A, playing a crucial role in late endosomal trafficking and the recycling of cellular components RAB9B is involved in the transport of cargo from the late endosomes to the Golgi network, facilitating the sorting of proteins and lipids within the cell It regulates the internalization and recycling of membrane-bound proteins, helping to maintain the composition of the plasma membrane and the function of various receptors on the cell surface RAB9B also plays a role in regulating the immune response and inflammation by controlling the trafficking of immune receptors Disruptions in RAB9B’s function are associated with diseases related to defective vesicular trafficking, including cancer, where abnormal cell signaling and vesicle transport contribute to tumor growth and metastasis Furthermore, RAB9B has been implicated in neurodegenerative conditions, where impaired protein sorting and degradation lead to the accumulation of toxic substances within cells

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