RAB9B antibody

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935106861
info@markelab.com
name
RAB9B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07050
tested applications
ELISA, WB, IF

Description

Involved in the transport of proteins between the endosomes and the trans Golgi network.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
RAB9B, member RAS oncogene family (RAB9B)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
23-25 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9NP90
Gene ID
51209
Alias
RAB9L,Rab-9-like protein,Ras-related protein Rab-9B
Background
Antibody anti-RAB9B
Status
RUO
Note
Mol. Weight 23-25 kDa

Descripción

RAB9B, member RAS oncogene family (RAB9B) shares functional similarities with RAB9A, playing a crucial role in late endosomal trafficking and the recycling of cellular components RAB9B is involved in the transport of cargo from the late endosomes to the Golgi network, facilitating the sorting of proteins and lipids within the cell It regulates the internalization and recycling of membrane-bound proteins, helping to maintain the composition of the plasma membrane and the function of various receptors on the cell surface RAB9B also plays a role in regulating the immune response and inflammation by controlling the trafficking of immune receptors Disruptions in RAB9B’s function are associated with diseases related to defective vesicular trafficking, including cancer, where abnormal cell signaling and vesicle transport contribute to tumor growth and metastasis Furthermore, RAB9B has been implicated in neurodegenerative conditions, where impaired protein sorting and degradation lead to the accumulation of toxic substances within cells

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