RAB7B, Member RAS Oncogene Family (RAB7B) Antibody
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Description
RAB7B Antibody is a Rabbit Polyclonal against RAB7B.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB7B, Member RAS Oncogene Family (RAB7B) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96AH8 |
| Gene ID | 338382 |
| Alias | RAB7,Ras-related protein Rab-7b |
| Background | Antibody anti-RAB7B |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
RAB7B, member RAS oncogene family (RAB7B) is a member of the RAS family of GTPases that plays a vital role in regulating vesicular trafficking, particularly in late endosomes and lysosomes RAB7B is involved in the maturation of endosomes and the transport of vesicles to the lysosome for degradation and recycling, a crucial process for maintaining cellular homeostasis It also plays a role in regulating autophagy, the cellular mechanism for degrading damaged or unnecessary organelles and proteins Disruptions in RAB7B function are linked to several diseases, including neurodegenerative disorders, where impaired vesicular trafficking leads to the accumulation of toxic proteins and damaged cellular components Additionally, RAB7B is involved in regulating cell survival, immune response, and inflammation, making it a key player in cellular responses to stress and infection
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