Controls vesicular trafficking from endosomes to the trans-Golgi network(TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF-and EGFR degradation pathway.
Primary Antibodies
polyclonal
human,mouse
RAB7B, member RAS oncogene family
Rabbit
IgG
Unconjugated
liquid
ELISA, WB
23 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:2000
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
RAB7B
RAB7,Ras-related protein Rab-7b
This product is for research use only.
Controls vesicular trafficking from endosomes to the trans-Golgi network(TGN). Acts as a negative regulator of TLR9 sign...
Precio a consultar
Ver másProtein transport. Probably involved in vesicular traffic (By similarity).
250€ (80 µl)
Ver másRAB7B Antibody is a Rabbit Polyclonal against RAB7B.
350€ (100 µg)
Ver más