Ras-Related Protein Rab-6A (RAB6A) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
Ras-Related Protein Rab-6A (RAB6A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014800
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against RAB6A protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Ras-Related Protein Rab-6A (RAB6A) Immunogen: The antiserum was produced against synthesized peptide derived from internal of human RAB6A. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/20000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P20340 |
| Gene ID | 5870 |
| OMIM | 179513 |
| Alias | RAB6,Ras-related protein Rab-6A |
| Background | Antibody anti-RAB6A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
RAB6A, member RAS oncogene family (RAB6A) is another small GTPase in the RAS superfamily that is involved in regulating intracellular vesicular trafficking, particularly in the post-Golgi network RAB6A plays a critical role in the movement of vesicles from the Golgi to the plasma membrane and the sorting of secretory proteins It is involved in regulating vesicular recycling, protein transport, and the proper trafficking of signaling molecules within the cell RAB6A has also been implicated in controlling the organization of the microtubule network and in regulating the cell cycle, especially during mitosis Alterations in RAB6A expression or function are linked to several diseases, including cancer, where dysregulated vesicle trafficking and cell cycle progression contribute to tumorigenesis RAB6A’s role in regulating cellular communication and secretion further highlights its importance in both normal cellular function and the pathogenesis of various diseases
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