RAB6A antibody
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Description
Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum(ER). Has a low GTPase activity.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB6A, member RAS oncogene family (RAB6A) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 24 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P20340 |
| Gene ID | 5870 |
| Alias | RAB6,Ras-related protein Rab-6A |
| Background | Antibody anti-RAB6A |
| Status | RUO |
| Note | Mol. Weight 24 kDa |
Descripción
RAB6A, member RAS oncogene family (RAB6A) is another small GTPase in the RAS superfamily that is involved in regulating intracellular vesicular trafficking, particularly in the post-Golgi network RAB6A plays a critical role in the movement of vesicles from the Golgi to the plasma membrane and the sorting of secretory proteins It is involved in regulating vesicular recycling, protein transport, and the proper trafficking of signaling molecules within the cell RAB6A has also been implicated in controlling the organization of the microtubule network and in regulating the cell cycle, especially during mitosis Alterations in RAB6A expression or function are linked to several diseases, including cancer, where dysregulated vesicle trafficking and cell cycle progression contribute to tumorigenesis RAB6A’s role in regulating cellular communication and secretion further highlights its importance in both normal cellular function and the pathogenesis of various diseases
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