RAB37, Member RAS Oncogene Family (RAB37) Antibody

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221€ (50 µg)

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935106861
info@markelab.com
name
RAB37, Member RAS Oncogene Family (RAB37) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx324743
tested applications
ELISA, WB, IHC

Description

RAB37 Antibody is a Rabbit Polyclonal against RAB37.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
RAB37, Member RAS Oncogene Family (RAB37)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/5000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q96AX2
Gene ID
326624
Alias
Ras-related protein Rab-37
Background
Antibody anti-RAB37
Status
RUO

Descripción

RAB37, member RAS oncogene family (RAB37) is a small GTPase involved in intracellular vesicular trafficking, particularly in the regulation of endocytosis and exocytosis RAB37 plays a crucial role in the sorting and recycling of proteins between different cellular compartments, ensuring that membrane-bound proteins, lipids, and other cargo are correctly processed and directed to their destinations This function is essential for maintaining cellular homeostasis, signal transduction, and membrane dynamics Additionally, RAB37 has been shown to play a role in autophagy, the process of degrading and recycling damaged or unnecessary cellular components to maintain cellular health Its dysfunction can contribute to several pathologies, including cancer and neurodegenerative diseases, where impaired vesicular trafficking leads to dysregulated cellular signaling and protein accumulation, contributing to disease progression

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