Rab26, Member Ras Oncogene Family (RAB26) Antibody
637€ (100 µl)
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Name
Rab26, Member Ras Oncogene Family (RAB26) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx114973
Tested Applications
ELISA, WB
Description
Rab26, Member Ras Oncogene Family Antibody is a Rabbit Polyclonal antibody against Rab26, Member Ras Oncogene Family.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Rab26, Member Ras Oncogene Family (RAB26) Immunogen: Human RAB26. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9ULW5 |
| Gene ID | 25837 |
| NCBI Accession | NP_001294982.1, NM_001308053.1, NP_055168.2, NM_014353.4 |
| OMIM | 605455 |
| Alias | V46133,Ras-related protein Rab-26 |
| Background | Antibody anti-RAB26 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RAB26, member RAS oncogene family (RAB26) is a GTPase that participates in regulating intracellular vesicle trafficking, contributing to processes such as protein sorting and membrane recycling RAB26 is involved in maintaining cellular homeostasis by controlling the trafficking of vesicles between cellular compartments, particularly in the endocytic and exocytic pathways It plays a role in the recycling of membrane proteins, ensuring proper receptor availability at the cell surface for signaling and internalization Furthermore, RAB26 is linked to the regulation of autophagy, the process by which cells degrade and recycle damaged organelles and proteins RAB26 helps in the proper sorting of proteins to the lysosomes, where they are degraded, contributing to cellular maintenance and stress responses This protein’s involvement in autophagy links it to diseases such as cancer and neurodegenerative disorders, where impaired vesicular trafficking and autophagy can lead to cellular dysfunction and disease progression In cancer, RAB26’s dysfunction may contribute to the accumulation of misfolded proteins and the promotion of tumor growth and metastasis
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