RAB26, Member RAS Oncogene Family (RAB26) Antibody

Product Graph
292.5€ (80 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
RAB26, Member RAS Oncogene Family (RAB26) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx029644
tested applications
ELISA, WB

Description

Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM].

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
RAB26, Member RAS Oncogene Family (RAB26)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified through a protein A column, followed by peptide affinity purification.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9ULW5
Alias
V46133,Ras-related protein Rab-26
Background
Antibody anti-RAB26
Status
RUO

Descripción

RAB26, member RAS oncogene family (RAB26) is a GTPase that participates in regulating intracellular vesicle trafficking, contributing to processes such as protein sorting and membrane recycling RAB26 is involved in maintaining cellular homeostasis by controlling the trafficking of vesicles between cellular compartments, particularly in the endocytic and exocytic pathways It plays a role in the recycling of membrane proteins, ensuring proper receptor availability at the cell surface for signaling and internalization Furthermore, RAB26 is linked to the regulation of autophagy, the process by which cells degrade and recycle damaged organelles and proteins RAB26 helps in the proper sorting of proteins to the lysosomes, where they are degraded, contributing to cellular maintenance and stress responses This protein’s involvement in autophagy links it to diseases such as cancer and neurodegenerative disorders, where impaired vesicular trafficking and autophagy can lead to cellular dysfunction and disease progression In cancer, RAB26’s dysfunction may contribute to the accumulation of misfolded proteins and the promotion of tumor growth and metastasis

Related Products

FNab07008

RAB26 antibody

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland.

Ver Producto
P6978

Recombinant Human RAB26

Ver Producto
abx029644

RAB26, Member RAS Oncogene Family (RAB26) Antibody

Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM].

Ver Producto