RAB20, Member RAS Oncogene Family (RAB20) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
RAB20, Member RAS Oncogene Family (RAB20) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014792
tested applications
WB
Description
Rabbit polyclonal antibody against RAB20 protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB20, Member RAS Oncogene Family (RAB20) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NX57 |
| Alias | Ras-related protein Rab-20 |
| Background | Antibody anti-RAB20 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
RAB20, member RAS oncogene family (RAB20) is another small GTPase in the RAB family that plays an essential role in regulating intracellular vesicle transport RAB20 is involved in the movement of vesicles between cellular compartments such as endosomes, lysosomes, and the plasma membrane, contributing to processes like endocytosis and vesicular recycling It helps ensure the proper sorting and trafficking of proteins and lipids to their correct cellular destinations, thereby maintaining cellular homeostasis and regulating key cellular processes like signaling, growth, and differentiation RAB20’s role in regulating vesicular trafficking is also crucial for processes like cytokinesis and cell division, where it helps ensure proper distribution of cellular components during mitosis Additionally, RAB20 has been implicated in controlling immune receptor trafficking, which affects cellular immune responses and inflammation RAB20’s dysfunction can contribute to various diseases, including immune-related disorders and cancers, by disrupting vesicular trafficking, immune signaling, and cellular mobility
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