Rab-7-Like Protein 1 (RAB7L1) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
Rab-7-Like Protein 1 (RAB7L1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014802
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against RAB7L1 protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Rab-7-Like Protein 1 (RAB7L1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/20000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O14966 |
| Alias | RAB7L,RAB7L1,Ras-related protein Rab-29,Rab-7-like protein 1,Ras-related protein Rab-7L1 |
| Background | Antibody anti-RAB29 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
RAB29, member RAS oncogene family (RAB29) is a small GTPase that regulates vesicular transport, particularly in the movement of vesicles between the Golgi apparatus and the plasma membrane RAB29 is essential for maintaining the intracellular trafficking system and ensures the proper distribution of membrane proteins, which are critical for maintaining cellular signaling, polarity, and adhesion It has been shown to contribute to the regulation of autophagy, aiding in the degradation and recycling of damaged cellular components RAB29’s involvement in autophagy links it to various stress response pathways and plays a role in protecting cells from oxidative damage and metabolic stress Furthermore, RAB29 has been implicated in regulating neuronal function, with defects in its activity associated with neurodegenerative diseases such as Parkinson's disease, where impaired autophagic clearance of misfolded proteins leads to cellular dysfunction In cancer, RAB29’s role in vesicular trafficking can affect tumor progression by altering the movement of key proteins involved in cell growth, migration, and metastasis
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