P2Y Purinoceptor 10 (P2RY10) Antibody
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Description
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. Two alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | P2Y Purinoceptor 10 (P2RY10) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O00398 |
| Alias | P2RY10,LPS2,P2Y10,LYPSR2 |
| Background | Antibody anti-P2RY10 |
| Status | RUO |
Descripción
P2RY10 is a G protein-coupled receptor (GPCR) within the P2Y family, classified as an orphan receptor due to the uncertainty surrounding its endogenous ligand. It is suspected to respond to lysophospholipids like lysophosphatidic acid (LPA) or sphingosine-1-phosphate (S1P), contributing to lipid signaling. P2RY10 is expressed in immune cells, including lymphocytes and tissues involved in the immune response, where it regulates cell migration, inflammation, and lymphocyte development. It has also been linked to roles in lipid metabolism and cellular signaling during tissue repair and immune activation. Dysregulation of P2RY10 has been associated with immune system disorders, such as autoimmune diseases, and it may also play a role in cancer progression due to its involvement in cell migration and proliferation. P2RY10 remains an emerging therapeutic target as its function becomes better understood, particularly in inflammation, immune regulation, and lipid signaling pathways.
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