Putative Butyrophilin Subfamily 2 Member A3 (BTN2A3) Antibody
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Description
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC) associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A3) and BTN3 (e.g., BNT3A1; MIM 613593) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010].
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Putative Butyrophilin Subfamily 2 Member A3 (BTN2A3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96KV6 |
| Alias | BTN2.3,BTN2A3,Putative butyrophilin subfamily 2 member A3 |
| Background | Antibody anti-BTN2A3P |
| Status | RUO |
Descripción
BTN2A3P is classified as a pseudogene within the butyrophilin family, meaning it does not encode a functional protein. However, pseudogenes like BTN2A3P can have regulatory roles, such as influencing the expression of related functional genes. BTN2A3P may modulate the activity of BTN2A1 and BTN2A2 or play roles in genomic architecture and evolution. Although its direct biological roles are less defined, it may contribute to immune regulation indirectly through gene expression networks.
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Putative Butyrophilin Subfamily 2 Member A3 (BTN2A3) Antibody
The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC) associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A3) and BTN3 (e.g., BNT3A1; MIM 613593) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010].
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