935106861
info@markelab.com
Precio
250€ (50 µl)
P2Y Purinoceptor 6 (P2RY6) Antibody is a Rabbit Polyclonal against P2RY6.
P2RY6 is a G protein-coupled receptor activated by extracellular UDP (uridine diphosphate) and to a lesser extent UTP, mediating cellular responses to nucleotide release during tissue injury or inflammation. P2RY6 couples primarily to Gq proteins, leading to phospholipase C (PLC) activation, calcium mobilization, and downstream signaling that regulates inflammation, immune responses, and smooth muscle contraction. P2RY6 is widely expressed in immune cells, smooth muscle, and epithelial tissues, where it modulates cytokine production, chemotaxis, and vascular tone. In inflammation, P2RY6 plays a central role in recruiting immune cells and amplifying inflammatory signaling, contributing to diseases such as asthma, arthritis, and colitis. It is also involved in smooth muscle contraction in the vascular and gastrointestinal systems. Dysregulation of P2RY6 signaling is linked to chronic inflammatory diseases, cardiovascular dysfunction, and metabolic disorders. P2RY6 antagonists are being investigated as therapeutic agents for inflammation, asthma, and vascular diseases due to their role in regulating immune and smooth muscle responses.
Primary Antibodies
Polyclonal
Human, Mouse, Rat
P2Y Purinoceptor 6 (P2RY6)
Rabbit
Unconjugated
Liquid
ELISA, WB, IHC
Antigen Affinity Chromatography.
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
50 µl
100 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
P2RY6
No
Shipped within 5-10 working days.
P2RY6,uridine nucleotide receptor,P2Y6,P2Y ATP receptor 6,P2Y purinoceptor 6,pyrimidinergic receptor P2Y
This product is for research use only.
Precio a consultar
Ver másReceptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a pho...
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Ver másP2Y Purinoceptor 6 (P2RY6) Antibody is a Rabbit Polyclonal antibody against P2RY6. The product of this gene belongs to t...
175€ (20 µl)
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