935106861
info@markelab.com
Precio
250€ (50 µl)
P2RY1 Antibody is a Rabbit Polyclonal against P2RY1.
P2RY1 is a G protein-coupled receptor (GPCR) that binds extracellular nucleotides such as ADP, acting as a key player in platelet aggregation, neurotransmission, and vascular tone. It couples to Gq proteins, activating phospholipase C (PLC) and increasing intracellular calcium levels, which triggers platelet activation and aggregation in response to ADP. P2RY1 is widely expressed in platelets, the central nervous system, and endothelial cells, where it regulates hemostasis, blood clot formation, and vasodilation. In the CNS, P2RY1 modulates neuronal excitability and synaptic transmission. Dysregulation of P2RY1 signaling is associated with thrombosis, stroke, and neuroinflammatory conditions. P2RY1 antagonists are being developed as antithrombotic agents to prevent clot formation in cardiovascular diseases. Its critical role in platelet function, vascular regulation, and neuroprotection highlights P2RY1 as a therapeutic target for thrombotic disorders and neurological diseases.
Primary Antibodies
Polyclonal
Human, Mouse, Rat
P2Y Purinoceptor 1 (P2RY1)
Rabbit
Unconjugated
Liquid
ELISA, IHC
Antigen Affinity Chromatography.
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
50 µl
100 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
P2RY1
No
Shipped within 5-10 working days.
P2RY1,ATP receptor,P2 purinoceptor subtype Y1,P2Y purinoceptor 1,platelet ADP receptor ,Purinergic receptor P2Y1,P2Y ATP receptor 1,P2Y1 receptor,purinergic receptor P2Y,P2Y1, SARCC
This product is for research use only.
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Ver másReceptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of...
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Ver másP2RY1 Antibody is a Rabbit Polyclonal Antibody against P2RY1.
175€ (20 µl)
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