Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Antibody
260€ (50 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx212471
tested applications
ELISA, IHC
Description
PTPRM Antibody is a Rabbit Polyclonal against PTPRM.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Protein Tyrosine Phosphatase Receptor Type M (PTPRM) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/2000 - 1/10000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P28827 |
| Gene ID | 5797 |
| Alias | RPTPM,RPTPU,PTPRL1,hR-PTPu,R-PTP-MU,Protein-tyrosine phosphatase mu,Receptor-type tyrosine-protein phosphatase mu |
| Background | Antibody anti-PTPRM |
| Status | RUO |
Descripción
PTPRM, also known as RPTPμ, is a receptor-like protein tyrosine phosphatase that regulates cell-cell adhesion, signaling, and growth suppression. Structurally, PTPRM contains extracellular Ig-like and fibronectin type III domains, a transmembrane domain, and two intracellular phosphatase domains. PTPRM mediates homophilic binding, meaning it interacts with other PTPRM molecules on adjacent cells to facilitate cell-cell adhesion. It plays essential roles in maintaining tissue architecture, especially in epithelial and endothelial cells. PTPRM interacts with cadherins and catenins to regulate cell adhesion and cytoskeletal organization. Loss or downregulation of PTPRM is associated with cancer progression and metastasis due to disrupted cell adhesion. Its regulatory role in neuronal guidance and tissue integrity also highlights its importance in development and cancer biology.
Related Products
Human Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Protein
Recombinant Protein Tyrosine Phosphatase Receptor Type M (PTPRM) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto
Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Antibody
Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type M (PTPRM).
Ver Producto
Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Antibody
PTPRM Antibody is a Rabbit Polyclonal against PTPRM.
Ver Producto