Human Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Protein
234€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx068776
tested applications
WB, SDS-PAGE
Description
Recombinant Protein Tyrosine Phosphatase Receptor Type M (PTPRM) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Protein Tyrosine Phosphatase Receptor Type M (PTPRM) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 27.6 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Thr1197-Ser1403 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P28827 |
| Alias | RPTPM,RPTPU,PTPRL1,hR-PTPu,R-PTP-MU,Protein-tyrosine phosphatase mu,Receptor-type tyrosine-protein phosphatase mu |
| Background | Protein PTPRM |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
PTPRM, also known as RPTPμ, is a receptor-like protein tyrosine phosphatase that regulates cell-cell adhesion, signaling, and growth suppression. Structurally, PTPRM contains extracellular Ig-like and fibronectin type III domains, a transmembrane domain, and two intracellular phosphatase domains. PTPRM mediates homophilic binding, meaning it interacts with other PTPRM molecules on adjacent cells to facilitate cell-cell adhesion. It plays essential roles in maintaining tissue architecture, especially in epithelial and endothelial cells. PTPRM interacts with cadherins and catenins to regulate cell adhesion and cytoskeletal organization. Loss or downregulation of PTPRM is associated with cancer progression and metastasis due to disrupted cell adhesion. Its regulatory role in neuronal guidance and tissue integrity also highlights its importance in development and cancer biology.
Related Products
Human Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Protein
Recombinant Protein Tyrosine Phosphatase Receptor Type M (PTPRM) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto
Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Antibody
Polyclonal Antibody to Protein Tyrosine Phosphatase Receptor Type M (PTPRM).
Ver Producto
Protein Tyrosine Phosphatase Receptor Type M (PTPRM) Antibody
PTPRM Antibody is a Rabbit Polyclonal against PTPRM.
Ver Producto