Protein Phosphatase 2 Regulatory Subunit Bbeta (PPP2R2B) Antibody
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Description
Rabbit polyclonal antibody against PPP2R2B protein. Immunogen region is Internal.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Protein Phosphatase 2 Regulatory Subunit Bbeta (PPP2R2B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/40000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q00005 |
| Background | Antibody anti-PPP2R2B |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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PPP2R2B antibody
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity(By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance(By similarity).
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Protein Phosphatase 2 Regulatory Subunit Bbeta (PPP2R2B) Antibody
Rabbit polyclonal antibody against PPP2R2B protein. Immunogen region is Internal.
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Protein Phosphatase 2 Regulatory Subunit Bbeta (PPP2R2B) Antibody
PPP2R2B belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This protein is a beta isoform of the regulatory subunit B55 subfamily.
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