PPP2R2B antibody
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Description
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity(By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | protein phosphatase 2(formerly 2A), regulatory subunit B, beta isoform (PPP2R2B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:1000; IP: 1:500-1:1000; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 52 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q00005 |
| Gene ID | 5521 |
| Alias | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform,PP2A subunit B isoform B55-beta,PP2A subunit B isoform PR55-beta,PP2A subunit B isoform R2-beta,PP2A subunit B isoform beta,PPP2R2B |
| Background | Antibody anti-PPP2R2B |
| Status | RUO |
| Note | Mol. Weight 52 kDa |
Descripción
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