Protein CBFA2T3 (CBFA2T3) Antibody
377€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Protein CBFA2T3 (CBFA2T3) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx231316
Tested Applications
ELISA, WB
Description
CBFA2T3 Antibody is a Rabbit Polyclonal against CBFA2T3.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Protein CBFA2T3 (CBFA2T3) Immunogen: core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 62-65 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75081 |
| Gene ID | 863 |
| OMIM | 603870 |
| Alias | ETO2,MTG16,MTGR2,ZMYND4,RUNX1T3,Zinc finger MYND domain-containing protein 4,Myeloid translocation gene on chromosome 16 protein |
| Background | Antibody anti-CBFA2T3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CBFA2/RUNX1 partner transcriptional co-repressor 3 (CBFA2T3) is another member of the CBFA2T family, acting as a co-repressor in the context of RUNX1-mediated transcription CBFA2T3 works similarly to CBFA2T2 by interacting with RUNX1 to repress gene expression, thereby playing a vital role in regulating hematopoietic development and function Like its counterpart, CBFA2T3 contributes to the maintenance of normal blood cell development by modulating gene expression that is essential for stem cell differentiation and lineage commitment It helps control processes like cell proliferation, differentiation, and apoptosis during hematopoiesis Mutations or alterations in CBFA2T3 expression can lead to hematologic disorders such as leukemia, where dysfunctional co-repression can disrupt the balance of cell growth and differentiation Understanding the role of CBFA2T3 in hematopoiesis could provide valuable insights into therapeutic strategies for blood cancers and other disorders related to abnormal gene regulation
Productos relacionados
Protein CBFA2T3 (CBFA2T3) Antibody
Core-Binding Factor, Runt Domain, Alpha Subunit 2; Translocated To, 3 Antibody is a Rabbit Polyclonal antibody against C…
Ver producto Protein CBFA2T3 (CBFA2T3) Antibody
CBFA2T3 Antibody is a Rabbit Polyclonal against CBFA2T3.…
Ver producto Protein CBFA2T3 (CBFA2T3) Antibody
CBFA2T3 Antibody is a Rabbit Polyclonal against CBFA2T3.…
Ver producto