Protein C Receptor, Endothelial (PROCR) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Protein C Receptor, Endothelial (PROCR) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx031769
Tested Applications
ELISA, WB, IHC, FCM
Description
PROCR (CD201) is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in its gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Protein C Receptor, Endothelial (PROCR) Immunogen: KLH-conjugated synthetic peptide between 104-132 amino acids from the Central region of human CD201. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 26.7 kDa |
| Purification | Purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UNN8 |
| Alias | CCCA,EPCR,CCD41,Endothelial protein C receptor, Activated protein C receptor,APC receptor,Endothelial cell protein C receptor |
| Background | Antibody anti-PROCR |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
PROCR, also known as the endothelial protein C receptor (EPCR), is a critical component of the protein C anticoagulant pathway. This pathway has essential roles in regulating blood coagulation, inflammation, and maintaining vascular integrity. PROCR is primarily expressed on endothelial cells lining blood vessels and binds to activated protein C (APC) to enhance its anticoagulant effects. This interaction is vital for limiting thrombosis, mitigating inflammation, and preserving the barrier function of blood vessels, especially in response to inflammatory and coagulatory challenges. Recent research has revealed additional roles for PROCR, including functions in immune response modulation, cell proliferation, and tissue regeneration.
Productos relacionados
Protein C Receptor, Endothelial (PROCR) Antibody
PROCR Antibody is a Rabbit Polyclonal antibody against PROCR. The protein encoded by this gene is a receptor for activat…
Ver producto Protein C Receptor, Endothelial (PROCR) Antibody
PROCR (CD201) is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulatio…
Ver producto
Human Protein C Receptor, Endothelial (PROCR) ELISA Kit
Human Protein C Receptor, Endothelial (PROCR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Hum…
Ver producto