Human Prosaposin (PSAP) Protein

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234€ (2 µg)

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935106861
info@markelab.com
name
Human Prosaposin (PSAP) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262664
tested applications
SDS-PAGE

Description

PSAP is a recombinant protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Prosaposin (PSAP)
Host
HEK293 cells
Origin
Human
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
2 µg
Size 2
10 µg
Size 3
1 mg
Form
Lyophilized
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
UniProt ID
P07602
Gene ID
5660
OMIM
176801
Background
Protein PSAP
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

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This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

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