Mouse PSAP (Prosaposin) ELISA Kit

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935106861
info@markelab.com
name
Mouse PSAP (Prosaposin) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM2515
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Mouse
Assay Type
Sandwich ELISA, Double Antibody
Test Range
31.2-2000pg/ml
Sensitivity
18.75pg/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
Q61207
Alias
PSAP, GLBA, SAP1, GLBA, proactivator polypeptide, prosaposin, sphingolipid activator protein-1
Background
Elisa kits for PSAP
Status
RUO

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PSAP antibody

This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

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