Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Antibody

Este producto es parte de PSG1 - pregnancy specific beta-1-glycoprotein 1
Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Antibody
221€ (50 µg)

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Name
Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx323770
Tested Applications
ELISA, WB

Description

PSG1 Antibody is a Rabbit Polyclonal against PSG1.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1)
Immunogen: Synthesized peptide derived from the Internal region of human PSG1.
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/20000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P11464
Gene ID
5669
Alias
SP1, B1G1,PBG1,CD66f,PSBG1,PSG95,PSGGA,DHFRP2,PSBG-1,PSGIIA,FL-NCA-1/2,PS-beta-C/D,PS-beta-G-1,Fetal liver non-specific cross-reactive antigen 1/2,Pregnancy-specific beta-1 glycoprotein C/D,Pregnancy-specific beta-1-glycoprotein 1
Background
Antibody anti-PSG1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

Pregnancy-specific beta-1-glycoprotein 1 (PSG1) is part of the pregnancy-specific glycoprotein (PSG) family, which belongs to the immunoglobulin (Ig) superfamily. These glycoproteins are encoded by a group of genes clustered on chromosome 19q13.2. PSG1 is the most abundantly expressed member of the PSG family during pregnancy and plays a crucial role in modulating the maternal immune system to ensure successful pregnancy outcomes. The PSG proteins are primarily produced by the syncytiotrophoblasts of the placenta and released into maternal circulation, where their levels rise significantly during pregnancy. They are considered placental hormones with immunomodulatory and angiogenic properties that help maintain the immunological tolerance of the fetus and support fetal development. PSG1, in particular, has been studied for its involvement in the regulation of immune tolerance, inhibition of inflammatory responses, and promotion of vascularization at the maternal-fetal interface. It is believed to have a key role in creating a favorable environment for fetal growth by modulating maternal immune responses and enhancing placental vascular development.

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