Human Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Protein
234€ (10 µg)
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name
Human Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx068658
tested applications
WB, SDS-PAGE
Description
Recombinant Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 26.7 kDa Observed MW (SDS-PAGE): 27 kDa Concentration: Prior to lyophilization: 100 µg/ml Sequence Fragment: Leu202-Thr401 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized Reconstitute in ddH2O to a concentration of 0.1-0.25 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 100 mM NaHCO<sub>3</sub>, 500 mM NaCl, pH 8.3, containing 0.01% Sarcosyl and 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P11464 |
| Gene ID | 5669 |
| OMIM | 176390 |
| Alias | SP1, B1G1,PBG1,CD66f,PSBG1,PSG95,PSGGA,DHFRP2,PSBG-1,PSGIIA,FL-NCA-1/2,PS-beta-C/D,PS-beta-G-1,Fetal liver non-specific cross-reactive antigen 1/2,Pregnancy-specific beta-1 glycoprotein C/D,Pregnancy-specific beta-1-glycoprotein 1 |
| Background | Protein PSG1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Pregnancy-specific beta-1-glycoprotein 1 (PSG1) is part of the pregnancy-specific glycoprotein (PSG) family, which belongs to the immunoglobulin (Ig) superfamily. These glycoproteins are encoded by a group of genes clustered on chromosome 19q13.2. PSG1 is the most abundantly expressed member of the PSG family during pregnancy and plays a crucial role in modulating the maternal immune system to ensure successful pregnancy outcomes. The PSG proteins are primarily produced by the syncytiotrophoblasts of the placenta and released into maternal circulation, where their levels rise significantly during pregnancy. They are considered placental hormones with immunomodulatory and angiogenic properties that help maintain the immunological tolerance of the fetus and support fetal development. PSG1, in particular, has been studied for its involvement in the regulation of immune tolerance, inhibition of inflammatory responses, and promotion of vascularization at the maternal-fetal interface. It is believed to have a key role in creating a favorable environment for fetal growth by modulating maternal immune responses and enhancing placental vascular development.
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Human PSG1(Pregnancy-specific beta-1-glycoprotein 1) ELISA Kit
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anti- PSG1 antibody
The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).
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