Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Antibody
273€ (100 µl)
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935106861
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name
Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx104138
tested applications
WB, IHC, IF/ICC
Description
Polyclonal Antibody to Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-5 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P11464 |
| Gene ID | 5669 |
| OMIM | 176390 |
| Alias | SP1, B1G1,PBG1,CD66f,PSBG1,PSG95,PSGGA,DHFRP2,PSBG-1,PSGIIA,FL-NCA-1/2,PS-beta-C/D,PS-beta-G-1,Fetal liver non-specific cross-reactive antigen 1/2,Pregnancy-specific beta-1 glycoprotein C/D,Pregnancy-specific beta-1-glycoprotein 1 |
| Background | Antibody anti-PSG1 |
| Status | RUO |
Descripción
Pregnancy-specific beta-1-glycoprotein 1 (PSG1) is part of the pregnancy-specific glycoprotein (PSG) family, which belongs to the immunoglobulin (Ig) superfamily. These glycoproteins are encoded by a group of genes clustered on chromosome 19q13.2. PSG1 is the most abundantly expressed member of the PSG family during pregnancy and plays a crucial role in modulating the maternal immune system to ensure successful pregnancy outcomes. The PSG proteins are primarily produced by the syncytiotrophoblasts of the placenta and released into maternal circulation, where their levels rise significantly during pregnancy. They are considered placental hormones with immunomodulatory and angiogenic properties that help maintain the immunological tolerance of the fetus and support fetal development. PSG1, in particular, has been studied for its involvement in the regulation of immune tolerance, inhibition of inflammatory responses, and promotion of vascularization at the maternal-fetal interface. It is believed to have a key role in creating a favorable environment for fetal growth by modulating maternal immune responses and enhancing placental vascular development.
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Human PSG1(Pregnancy-specific beta-1-glycoprotein 1) ELISA Kit
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anti- PSG1 antibody
The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).
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