Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Antibody
169€ (20 µl)
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Name
Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx320257
Tested Applications
ELISA, IHC, IP
Description
PSG1 Antibody is a Rabbit Polyclonal against PSG1.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Pregnancy Specific Beta-1-Glycoprotein 1 (PSG1) Immunogen: Recombinant human Pregnancy-specific beta-1-glycoprotein 1 protein (180-419AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200, IP: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IP |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P11464 |
| Gene ID | 5669 |
| NCBI Accession | NP_001171754.1, NM_001184825.1 |
| OMIM | 176390 |
| Alias | SP1, B1G1,PBG1,CD66f,PSBG1,PSG95,PSGGA,DHFRP2,PSBG-1,PSGIIA,FL-NCA-1/2,PS-beta-C/D,PS-beta-G-1,Fetal liver non-specific cross-reactive antigen 1/2,Pregnancy-specific beta-1 glycoprotein C/D,Pregnancy-specific beta-1-glycoprotein 1 |
| Background | Antibody anti-PSG1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Pregnancy-specific beta-1-glycoprotein 1 (PSG1) is part of the pregnancy-specific glycoprotein (PSG) family, which belongs to the immunoglobulin (Ig) superfamily. These glycoproteins are encoded by a group of genes clustered on chromosome 19q13.2. PSG1 is the most abundantly expressed member of the PSG family during pregnancy and plays a crucial role in modulating the maternal immune system to ensure successful pregnancy outcomes. The PSG proteins are primarily produced by the syncytiotrophoblasts of the placenta and released into maternal circulation, where their levels rise significantly during pregnancy. They are considered placental hormones with immunomodulatory and angiogenic properties that help maintain the immunological tolerance of the fetus and support fetal development. PSG1, in particular, has been studied for its involvement in the regulation of immune tolerance, inhibition of inflammatory responses, and promotion of vascularization at the maternal-fetal interface. It is believed to have a key role in creating a favorable environment for fetal growth by modulating maternal immune responses and enhancing placental vascular development.
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