Pregnancy-Associated Glycoprotein 1 (PAG1) Antibody

364€ (100 µg)
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935106861
info@markelab.com
name
Pregnancy-Associated Glycoprotein 1 (PAG1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx236112
tested applications
ELISA, WB
Description
PAG1 Antibody is a Rabbit Polyclonal against PAG1.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Pregnancy-Associated Glycoprotein 1 (PAG1) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | ≥ 95% (SDS-PAGE) |
Purification | Purified by immunogen affinity chromatography. |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9NWQ8 |
Gene ID | 55824 |
OMIM | 605767 |
Alias | PAG1, CBP, PAG, phosphoprotein membrane anchor with glycosphingolipid microdomains 1 |
Background | Antibody anti-PAG1 |
Status | RUO |
Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Pregnancy Associated Glycoprotein 1 (PAG1) belongs to a family of aspartic proteinases expressed by the placental trophoblasts in ruminant species. PAG1 is secreted into maternal circulation during pregnancy and serves as a marker of placental function and fetal well-being. It plays a role in modulating immune tolerance during pregnancy by potentially interacting with maternal immune cells to prevent rejection of the fetal allograft. PAG1 has been widely studied in veterinary medicine as a non-invasive biomarker for early pregnancy detection in cattle, sheep, and other ruminants. Its expression profile and stability in circulation make it a useful tool in reproductive management.
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