Phosphoprotein Associated With Glycosphingolipid Microdomains 1 (PAG1) Antibody
286€ (100 µl)
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Name
Phosphoprotein Associated With Glycosphingolipid Microdomains 1 (PAG1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx129786
Tested Applications
IHC
Description
Phosphoprotein Associated With Glycosphingolipid Microdomains 1 Antibody is a Rabbit Polyclonal against Phosphoprotein Associated With Glycosphingolipid Microdomains 1.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Phosphoprotein Associated With Glycosphingolipid Microdomains 1 (PAG1) Immunogen: PAG1 (Gly160-Gln390) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB (Predicted): 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | PAG1, CBP, PAG, phosphoprotein membrane anchor with glycosphingolipid microdomains 1 |
| Background | Antibody anti-PAG1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Pregnancy Associated Glycoprotein 1 (PAG1) belongs to a family of aspartic proteinases expressed by the placental trophoblasts in ruminant species. PAG1 is secreted into maternal circulation during pregnancy and serves as a marker of placental function and fetal well-being. It plays a role in modulating immune tolerance during pregnancy by potentially interacting with maternal immune cells to prevent rejection of the fetal allograft. PAG1 has been widely studied in veterinary medicine as a non-invasive biomarker for early pregnancy detection in cattle, sheep, and other ruminants. Its expression profile and stability in circulation make it a useful tool in reproductive management.
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