Pigment epithelium-derived factor (SERPINF1) Antibody (Biotin)
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Description
Pigment epithelium-derived factor (SERPINF1) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin for the detection of Human SERPINF1.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Pigment epithelium-derived factor (SERPINF1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purification | Purified by antigen affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P36955 |
| Gene ID | 5176 |
| OMIM | 172860 |
| Alias | OI6,OI12,PEDF,EPC-1,PIG35,Pigment epithelium-derived factor,Cell proliferation-inducing gene 35 protein,Serpin F1 |
| Background | Antibody anti-SERPINF1 |
| Status | RUO |
Descripción
SERPINF1, also known as pigment epithelium-derived factor (PEDF), is a member of the serpin (serine protease inhibitor) family, though it has unique properties distinct from classical serpins. Unlike most serpins, SERPINF1 does not function as a typical protease inhibitor but is instead a multifunctional protein with potent anti-angiogenic, neuroprotective, and anti-inflammatory effects. First identified in the pigment epithelium of the eye, it has since been found in a variety of tissues and is now recognized as a crucial player in many biological processes, including the inhibition of abnormal blood vessel growth and tissue protection. SERPINF1 is highly expressed in the eye, particularly in the retinal pigment epithelium (RPE) and other neural tissues. It is most famous for its role in ocular health, but its functions extend to other organs, such as the liver, heart, skin, and brain.
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