Phospholipase ABHD3 (ABHD3) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Phospholipase ABHD3 (ABHD3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx027632
tested applications
ELISA, WB
Description
This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Phospholipase ABHD3 (ABHD3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8WU67 |
| Alias | LABH3 |
| Background | Antibody anti-ABHD3 |
| Status | RUO |
Descripción
ABHD3 is a serine hydrolase that plays a significant role in lipid metabolism by hydrolyzing medium- and long-chain fatty acid esters of lysophosphatidylcholine (LPC), a major bioactive lipid. Expressed in tissues such as the liver, lungs, and brain, ABHD3 regulates LPC levels, thereby influencing inflammation, cell signaling, and membrane fluidity. The enzyme is involved in maintaining lipid homeostasis, ensuring balanced levels of bioactive lipids to prevent lipid-mediated toxicity and cellular stress. Dysregulation of ABHD3 has been associated with chronic inflammatory diseases and metabolic disorders, highlighting its critical role in modulating lipid-related processes. ABHD3 also interacts with other lipid-metabolizing enzymes to fine-tune lipid signaling pathways, making it a potential target for therapeutic intervention in diseases involving inflammation, lipid dysregulation, and membrane dysfunction. Its structural design emphasizes its specificity and efficiency in lipid hydrolysis, underscoring its functional importance in cellular health.
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