PIK3IP1 is a novel protein that shares homology with the p85 subunit of phosphatidylinositol-3-Kinases (PI3Ks). The PI3K is essential for cell proliferation and Survival. The PIK3IP down regulates the activity of the PI3K and induces apoptosis by associating with p85 and p110 to form a complex, using the p85-like domain. However, there is no evidence to suggest that the PIK3IP1 prevents association of p85 and p110 as they associate with very high affinity.
Primary Antibodies
Polyclonal
Human
Phosphoinositide-3-Kinase Interacting Protein 1 (PIK3IP1)
Rabbit
Unconjugated
Liquid
ELISA, WB
Purified through a protein A column, followed by peptide affinity purification.
PBS containing 0.09% sodium azide.
80 µl
400 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
PIK3IP1
No
Shipped within 5-10 working days.
This product is for research use only.
Negative regulator of hepatic phosphatidylinositol 3-kinase(PI3K) activity.
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281.25€ (80 µl)
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