PIK3IP1 antibody

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935106861
info@markelab.com
name
PIK3IP1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06452
tested applications
ELISA, WB, IP

Description

Negative regulator of hepatic phosphatidylinositol 3-kinase(PI3K) activity.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
phosphoinositide-3-kinase interacting protein 1 (PIK3IP1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
28 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q96FE7
Gene ID
113791
Alias
Phosphoinositide-3-kinase-interacting protein 1 (PI3K-interacting protein 1),Kringle domain-containing protein HGFL,PIK3IP1,HGFL
Background
Antibody anti-PIK3IP1
Status
RUO
Note
Mol. Weight 28-40 kDa

Descripción

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PIK3IP1 is a novel protein that shares homology with the p85 subunit of phosphatidylinositol-3-Kinases (PI3Ks). The PI3K is essential for cell proliferation and Survival. The PIK3IP down regulates the activity of the PI3K and induces apoptosis by associating with p85 and p110 to form a complex, using the p85-like domain. However, there is no evidence to suggest that the PIK3IP1 prevents association of p85 and p110 as they associate with very high affinity.

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