Oxysterols Receptor LXR-Beta (NR1H2) Antibody
351€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Oxysterols Receptor LXR-Beta (NR1H2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx375969
Tested Applications
ELISA, WB
Description
Oxysterols Receptor LXR-Beta (NR1H2) Antibody is a Rabbit Polyclonal antibody against Oxysterols Receptor LXR-Beta (NR1H2).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Oxysterols Receptor LXR-Beta (NR1H2) Immunogen: Synthesized peptide derived from part region of human protein |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P55055 |
| Gene ID | 7376 |
| Alias | NER,UNR,LXRB,LXR-b,NER-I,RIP15,Oxysterols receptor LXR-beta,Liver X receptor beta,Nuclear receptor NER |
| Background | Antibody anti-NR1H2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Nuclear receptor subfamily 1 group H member 2 (NR1H2), also known as LXRα (liver X receptor alpha), is a nuclear receptor involved in regulating lipid metabolism, cholesterol homeostasis, and immune response NR1H2 is primarily expressed in tissues such as the liver, adipose tissue, and macrophages, where it regulates genes involved in the absorption, storage, and catabolism of cholesterol and lipids LXRα plays a key role in maintaining cholesterol balance by promoting the expression of genes that enhance cholesterol efflux and inhibit cholesterol biosynthesis It also regulates inflammatory pathways, influencing the immune system's response to atherosclerosis and other chronic inflammatory diseases Dysregulation of NR1H2 signaling has been associated with cardiovascular diseases, such as atherosclerosis, where improper lipid metabolism leads to the accumulation of cholesterol plaques in blood vessels LXRα is also a potential therapeutic target for managing metabolic diseases, inflammation, and lipid-related disorders
Productos relacionados
Oxysterols Receptor LXR-Beta (NR1H2) Antibody
The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are k…
Ver producto Oxysterols Receptor LXR-Beta (NR1H2) Antibody
Nuclear Receptor Subfamily 1, Group H, Member 2 Antibody is a Rabbit Polyclonal antibody against Nuclear Receptor Subfam…
Ver producto
Oxysterols Receptor LXR-Beta (NR1H2) Antibody
Liver X Receptor Beta Antibody is a Rabbit Polyclonal against Liver X Receptor Beta.…
Ver producto