OPN-a / b Antibody
292.5€ (80 µl)
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935106861
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name
OPN-a / b Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx026330
tested applications
ELISA, WB, IHC, IF/ICC
Description
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity (By similarity).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | OPN-a/b |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P10451 |
| Alias | OPN5,opsin 5,transmembrane protein 13,GPR136,PGR12,neuropsin,PGR14,TMEM13,G protein-coupled receptor 136 |
| Background | Antibody anti-OPN5 |
| Status | RUO |
Descripción
Opsin-5, also known as OPN5, is a recently discovered opsin protein involved in non-visual light sensing. It belongs to the family of opsins that are sensitive to light but are not involved in traditional vision processes like those in rod and cone cells. OPN5 is thought to play a role in various physiological processes, such as regulating circadian rhythms, influencing mood, and potentially modulating the response to light in certain tissues. Unlike opsins involved in visual photoreception, OPN5 is activated by light in the ultraviolet and blue regions of the spectrum. Its expression has been identified in several tissues, including the brain and skin, where it likely contributes to the body's light-responsive mechanisms. OPN5 may play a role in regulating sleep-wake cycles, similar to melanopsin, but it is less understood. Further research into OPN5's specific functions and its mechanisms of action could provide new insights into how the body processes light outside the visual system and how light exposure affects various biological rhythms and behaviors.
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OPN-a / b Antibody
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity (By similarity).
Ver Producto