OPN-a / b Antibody

Este producto es parte de OPN - Opsin receptors
OPN-a / b Antibody

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935106861

info@markelab.com

Precio

292.5€ (80 µl)

Antibody anti-OPN5

proveedor

Abbexa

reference

abx026330

Tested Applications

ELISA, WB, IHC, IF/ICC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity (By similarity).


Background

Opsin-5, also known as OPN5, is a recently discovered opsin protein involved in non-visual light sensing. It belongs to the family of opsins that are sensitive to light but are not involved in traditional vision processes like those in rod and cone cells. OPN5 is thought to play a role in various physiological processes, such as regulating circadian rhythms, influencing mood, and potentially modulating the response to light in certain tissues. Unlike opsins involved in visual photoreception, OPN5 is activated by light in the ultraviolet and blue regions of the spectrum. Its expression has been identified in several tissues, including the brain and skin, where it likely contributes to the body's light-responsive mechanisms. OPN5 may play a role in regulating sleep-wake cycles, similar to melanopsin, but it is less understood. Further research into OPN5's specific functions and its mechanisms of action could provide new insights into how the body processes light outside the visual system and how light exposure affects various biological rhythms and behaviors.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

OPN-a/b


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB, IHC, IF/ICC


purification

Purified through a protein A column, followed by peptide affinity purification.


recommended dilution

WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.


buffer

PBS containing 0.09% sodium azide.


size 1

80 µl


size 2

400 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

OPN5


dry ice

No


availability

Shipped within 5-10 working days.


alias

OPN5,opsin 5,transmembrane protein 13,GPR136,PGR12,neuropsin,PGR14,TMEM13,G protein-coupled receptor 136


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