Neuropsin Cleaved-Val33 (OPN5 Cleaved-V33) Antibody
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935106861
info@markelab.com
Precio
52€ (10 µg)
Antibody anti-OPN5
proveedor
Abbexareference
abx015610Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Rabbit polyclonal antibody against Neuropsin protein. Immunogen region is N-terminal. Specificity is as follows for the reactive species: H:V33.
Background
Opsin-5, also known as OPN5, is a recently discovered opsin protein involved in non-visual light sensing. It belongs to the family of opsins that are sensitive to light but are not involved in traditional vision processes like those in rod and cone cells. OPN5 is thought to play a role in various physiological processes, such as regulating circadian rhythms, influencing mood, and potentially modulating the response to light in certain tissues. Unlike opsins involved in visual photoreception, OPN5 is activated by light in the ultraviolet and blue regions of the spectrum. Its expression has been identified in several tissues, including the brain and skin, where it likely contributes to the body's light-responsive mechanisms. OPN5 may play a role in regulating sleep-wake cycles, similar to melanopsin, but it is less understood. Further research into OPN5's specific functions and its mechanisms of action could provide new insights into how the body processes light outside the visual system and how light exposure affects various biological rhythms and behaviors.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Neuropsin Cleaved-Val33 (OPN5 Cleaved-V33)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
recommended dilution
WB: 1/500 - 1/3000, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
size 1
10 µg
size 2
100 µg
size 3
200 µg
size 4
300 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
OPN5
dry ice
No
availability
Shipped within 5-10 working days.
alias
OPN5,opsin 5,transmembrane protein 13,GPR136,PGR12,neuropsin,PGR14,TMEM13,G protein-coupled receptor 136
uniprot id
note
Concentration: 1 mg/ml -
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
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