Opioid-binding protein/cell adhesion molecule (OPCML) Antibody (FITC)
260€ (50 µl)
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Name
Opioid-binding protein/cell adhesion molecule (OPCML) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx346169
Description
Opioid-binding protein/cell adhesion molecule (OPCML) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human OPCML.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Opioid-binding protein/cell adhesion molecule (OPCML) Immunogen: Recombinant Human Opioid-binding protein/cell adhesion molecule protein (28-322 AA) |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 1 ml |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q14982 |
| Gene ID | 4978 |
| Alias | OPCM,OBCAM,IGLON1,IgLON family member 1,Opioid-binding cell adhesion molecule |
| Background | Antibody anti-OPCML |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Opioid binding protein/cell adhesion molecule-like (OPCML) is a member of the IgLON family of cell adhesion molecules (CAMs), which play essential roles in cell-cell communication and adhesion. OPCML was initially identified due to its ability to bind opioids, which suggested a potential role in the modulation of opioid signaling. However, subsequent research has revealed that its primary function lies in cell adhesion and tumor suppression. OPCML is encoded by the OPCML gene located on chromosome 11q25. This gene is highly conserved across species, indicating its crucial role in cellular processes. OPCML is ubiquitously expressed in various tissues, including the brain, where it participates in neural cell adhesion and signaling. In recent years, OPCML has gained attention due to its tumor suppressor functions and its involvement in several cancers.
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