Opioid Binding Protein/cell Adhesion Molecule Like (OPCML) Antibody
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Description
Rabbit Polyclonal against the OPCML protein.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Opioid Binding Protein/cell Adhesion Molecule Like (OPCML) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | OPCM,OBCAM,IGLON1,IgLON family member 1,Opioid-binding cell adhesion molecule |
| Background | Antibody anti-OPCML |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Opioid binding protein/cell adhesion molecule-like (OPCML) is a member of the IgLON family of cell adhesion molecules (CAMs), which play essential roles in cell-cell communication and adhesion. OPCML was initially identified due to its ability to bind opioids, which suggested a potential role in the modulation of opioid signaling. However, subsequent research has revealed that its primary function lies in cell adhesion and tumor suppression. OPCML is encoded by the OPCML gene located on chromosome 11q25. This gene is highly conserved across species, indicating its crucial role in cellular processes. OPCML is ubiquitously expressed in various tissues, including the brain, where it participates in neural cell adhesion and signaling. In recent years, OPCML has gained attention due to its tumor suppressor functions and its involvement in several cancers.
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